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Side effects of triple therapy H pylori treatment

The side effects of triple therapy H pylori treatment vary widely and can be pretty nasty, if I’m honest.

I didn’t take triple therapy when I had H pylori – I decided on a more natural, herb-based approach.

But we’ve received hundreds of emails (thousands, most probably) from frustrated people having a really hard time on triple therapy.

As I’ve said before: I don’t necessarily disagree with triple therapy, but I want to raise awareness of its drawbacks so folk like you can make informed decisions on what to do.

I’ll be a happy man if you can avoid feeling really bad during treatment, and minimize your chances of developing other symptoms as a result of triple therapy

This article emphasizes some of the main problems associated with taking triple therapy that you might not hear about from your doc.

As always, there’s a video followed by some writing – it won’t take you long to consume (I apologize for the sound on this one – it’s not great so please turn up the volume on your computer).

H pylori treatment doesn’t always work

One of the most frustrating things about H pylori treatment is that a lot of docs assume it works every time.

It doesn’t.

In fact, research shows clearly that triple therapy works about 70% of the time.

Some studies even show success rates as low as 50%.

I don’t say this to seem cool or suggest that antibiotics shouldn’t be used for H pylori treatment.

I’m simply sharing the info with you so that you have a balance of data on which to base your treatment decisions.

For those of you who’d like to see the research, it’s here.

Side effects of triple therapy H pylori treatment

Without doubt there a abundant side effects with H pylori treatment – it’s a common complaint.

Not everyone has side effects, and they can be mild or severe depending on each individual.

Because you’re taking 2, 3 and sometimes 4 different drugs (as in quadruple therapy), there are three or four reasons for side effects to develop.

The most frequently reported side effects of triple therapy H pylori treatment are:

  • Nausea
  • Vomiting
  • Metal taste in mouth
  • Glossitis (painful, inflamed tongue)
  • Abdominal pain and cramps
  • Diarrhoea
  • Urticaria (hives)

Other side effects include:

  • Fatigue
  • Depression
  • Heartburn and acid reflux
  • Sleep disruption
  • Alterations in mood
  • Joint and muscle pain
  • Headaches
  • Painful and tender liver / right shoulder blade area

You can read a study that reported triple therapy side effects in just over 200 patients here.

In this study, around 15% of the patients had side effects, and several of them could not complete their treatment as a result.

H pylori triple therapy can cause other problems

It’s known in the medical literature that triple therapy can trigger other problems, including:

  • Small intestinal bacterial overgrowth (SIBO)
  • Candida overgrowth
  • Clostridium difficile infection (especially in hospitals)
  • Possible parasite infection

It does this be disrupting your good, bacteria levels (also known as predominant bacteria).

The use of acid-blocking medication for 30-days can also suppress stomach acid levels to such an extent that

The range of symptoms you’ll feel from these additional problems include:

  • Heartburn and acid reflux
  • Bad breath
  • Bloated stomach and abdomen
  • Digestive pain
  • Constipation
  • Gas
  • Diarrhoea

Things like SIBO and Candida are also associated with:

  • Arthritis
  • Fibromyalgia
  • Depression
  • Migraine
  • Skin problems
  • Daily fatigue and energy problems
  • Dandruff
  • Fungal nails
  • Thrush (oral and vaginal)

It’s possible to prevent, or certainly vastly reduce your risk of developing them, by adding probiotics and gut healing supplements to your triple therapy regimen.

Or, of course, you can choose a natural approach from start to finish using dietary changes and herbs.

I want you to minimize your chances of developing antibiotic resistance

The main reason why H pylori triple therapy treatment fails in 30-35% of people is that H pylori is rapidly becoming more resistant to antibiotics.

Two excellent books have been written on this topic in the last few years.

“The Drugs Don’t Work” was written by Prof. Dame Sally Davis, who is the Chief Medical Officer in England.

Prof. Davis is a heavy hitter. She’s pretty much the head honcho in the medical system and says we’re heading for an “antibiotic apocalypse” if we’re not careful.

She suggests that in the next 10-20 years most of the antibiotics currently used won’t work against common infections.

She also points out that the drug companies simply aren’t developing new antibiotics to combat the increase in bacterial resistance.

“Missing Microbes” by Dr. Martin Blazer shows how the use of antibiotics severely disrupts our digestive ecosystem and opens us up to more problems than they solve.

Neither of these authors suggests that antibiotics aren’t useful.

Rather, it’s a case of only using them when necessary, i.e. when there’s a very serious infection or when symptoms are unbearable.

Given that H pylori, various other bacterial organisms, and parasites respond really well to herbal protocols, probiotics and detoxification strategies, it’s arguable whether antibiotics are needed in most cases.

Side effects of triple therapy H pylori treatment – summary

Don’t get mad with me – I’m just the messenger.

The stats and research suggest that:

  • H pylori triple therapy works 70% of the time, at best (2012 stats)
  • The antibiotics and PPI meds cause quite a few side effects
  • They have the ability to cause Candida, C. difficile and SIBO problems
  • They increase the threat of further antibiotic resistance, which could be a massive problem in a few year’s time

It’s your choice

Anyone who tells you that alternative treatments don’t work simply doesn’t know the truth.

Having worked with several thousand people, I can tell you that antibiotics can be avoided, and you can safely overcome H pylori and your symptoms with a natural approach.

BUT, as you know, the antibiotics DO work for many people.

So it’s really up to you what you want to do.

We’re here to guide you through your journey, so let us know how we can help.

Of course, my H Pylori Diet ebook is a great starting point if you’re looking for a natural approach.

If you’d prefer to talk to someone about your individual situation, we’ll lend a completely non-judgmental ear and talk to you for an hour.

I hope you’ve enjoyed this article on the side effects of triple therapy H pylori treatment!

Don’t forget that you can join the community discussion by leaving a comment below.



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